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Thursday, July 31, 2025

Chikungunya virus (CHIKV)

 Chikungunya virus (CHIKV)

   Chikungunya: it is important to stress that the disease is spread by mosquitoes in order to prevent it. It should be made clear that while it is not as deadly as malaria, its hallmark symptom is crippling joint pain. Since the name origin ("bent over") is memorable, I'll mention it.

Since dengue and Zika coexist in the same areas, it's crucial to differentiate between them. It's important to note that many locations are unable to test for it. Since treatment only addresses symptoms, management techniques are more important than medication.

We should identify current hotspots but refrain from raising unnecessary alarms because we may be concerned about outbreaks. Pregnancy risk is a prevalent issue that merits its own discussion. Concrete prevention advice should be given, such as reducing breeding sites, using certain repellents, and offering clothing advice.

     Chikungunya virus (CHIKV) is a mosquito-borne viral infection primarily transmitted by Aedes aegypti and Aedes albopictus mosquitoes (the same species that spread dengue and Zika). Here's a concise overview:

Key Facts:

  1. Origin:
    • First identified in Tanzania (1952).
    • The name comes from the Kimakonde language: "kungunyala" ("to become contorted"), describing severe joint pain.
  2. Transmission:
    • Primarily spread through mosquito bites (daytime-active mosquitoes).
    • Rarely: Mother-to-child during childbirth or via blood transfusion.

Symptoms:

Symptoms typically appear 3–7 days after a mosquito bite and include:

  • Sudden high fever (often >39°C / 102°F).
  • Severe joint pain:
    • It usually affects hands, wrists, ankles, and knees.
    • Can persist for weeks/months (chronic phase in 30-40% of cases).
  • Muscle pain and headache.
  • Rash (maculopapular, often on trunk/limbs).
  • Fatigue, nausea, or conjunctivitis.

Note:

  • Symptoms overlap with dengue and Zika, making lab testing essential.
  • Most patients recover fully, but joint pain may become chronic (months/years), especially in older adults.

For lab testing Find A Lab Near You

Complications (Rare but serious):

  • Neurologic issues (encephalitis, Guillain-Barré).
  • Heart inflammation or kidney failure.
  • Prolonged arthritis (may mimic rheumatoid arthritis).
  • Higher risk in: New-bornsolder adults (>65), and those with chronic conditions (e.g., hypertension, diabetes).

Prevention:

  • Mosquito control:
    • Eliminate standing water (breeding sites).
    • Use window screens and insecticide-treated bed nets.
  • Personal protection:
    • Apply EPA-registered repellents (DEET, picaridin).
    • Wear long sleeves/pants (light-colored).
  • Travel precautions:
    • Check CDC/WHO alerts for outbreaks (common in Africa, Asia, the Americas, and islands in the Indian/Pacific Oceans).

Public Health Impact:

  • Causes explosive outbreaks in tropical/subtropical regions.
  • No human-to-human transmission (except rare vertical/maternal-fetal cases).

If you experience symptoms after mosquito exposure (especially in endemic areas), consult a healthcare provider for testing and management.

For real-time outbreak updates: WHO Chikungunya | CDC Travel Health.

For lab testing Find A Lab Near You


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